BVD CONSULT

Genetic diversity of BVDV: Consequences for classification and molecular epidemiology

aUniversity of Veterinary Medicine, Department of Infectious Diseases and Parasitology, Komenskeho 73, 041 81 Kosice, Slovakia bUniversity of P.J. Safarik, Kosice, Slovakia cInstitute for Animal Health, Exotic Diseases Department, Pirbright, UK

Abstract

Genetic typing of bovine viral diarrhoea  virus (BVDV) is important for the precise classification of viruses as well as for the development of molecular epidemiology. BVDV isolates were usually typed based on comparison of genomic sequences from the 5′-untranslated region (5′-UTR), Npro and E2 region. Recently we have identified 11 genetic groups (subgenotypes) of BVDV-1. Our further experiments confirmed a new subgenotype, BVDV-1k, isolated from cattle in Switzerland. BVDV isolates from India were typed as BVDV-1b whereas BVDV-1c is a predominant subgenotype in Australia. The results of genetic typing of BVDV indicate that distribution of subgenotypes has no relationship to the geographic origin of viral isolates.

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This article was published in Preventive Veterinary Medicine, 72, S. Vilceka, B. Durkovica, M. Kolesarovab and D.J. Patonc, Genetic diversity of BVDV: Consequences for classification and molecular epidemiology, 31-35, Copyright Elsevier 2005.