Genetic heterogeneity of pestiviruses of ruminants in Switzerland

Institute of Veterinary Virology, University of Bern, Länggass-Str. 122, PO Box, CH-3001 Bern, Switzerland


We have genetically analyzed ruminant pestiviruses. All >150 bovine viral diarrhea (BVD)  viruses isolated from cattle in Switzerland belonged to genotype 1, with subgenogroups e, h, k and b found in decreasing frequency. To date, representatives of subgenogroup k have been detected in Switzerland only. Despite serological evidence of Border disease in sheep, only few Border disease viruses have been isolated, all of which belong to the novel group 3. Serological evidence suggested that pestivirus infections may occur also in wild ruminants in Switzerland but no isolates are available for analysis. In addition, we describe two pestiviruses, one a cell culture contaminant and the other isolated from a buffalo, that cluster with a recently proposed novel pestivirus species.


This article was published in Preventive Veterinary Medicine, 72, H.P. Stalder, Ph. Meier, G. Pfaffen, C. Wageck-Canal, J. Rüfenacht, P. Schaller, C. Bachofen, S. Marti, H.R. Vogt and E. Peterhans, Genetic heterogeneity of pestiviruses of ruminants in Switzerland, 37-41, Copyright Elsevier 2005.